KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAV2
All Species:
13.33
Human Site:
S787
Identified Species:
36.67
UniProt:
P52735
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52735
NP_001127870.1
878
101289
S787
R
S
P
A
S
C
A
S
Y
N
F
S
F
L
S
Chimpanzee
Pan troglodytes
XP_512321
790
91847
K700
N
S
L
K
D
C
F
K
S
L
D
T
T
L
Q
Rhesus Macaque
Macaca mulatta
XP_001099207
878
101303
S787
R
S
P
A
S
C
A
S
Y
N
F
S
F
L
G
Dog
Lupus familis
XP_850040
876
100535
S785
R
S
P
A
S
C
A
S
Y
N
F
S
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60992
868
99897
S777
R
S
P
A
S
C
A
S
Y
N
F
S
F
L
S
Rat
Rattus norvegicus
P54100
843
97935
C751
Q
Q
N
S
L
K
D
C
F
K
S
L
D
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505586
846
97900
Q755
S
L
K
E
S
F
K
Q
L
D
T
T
L
K
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NHV9
793
91337
V703
F
K
T
I
V
E
L
V
S
Y
Y
E
R
N
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q45FX5
1007
113536
L901
I
F
N
S
T
V
E
L
V
Q
Y
Y
R
S
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
99.6
90.2
N.A.
94.7
51.3
N.A.
83.7
N.A.
N.A.
N.A.
N.A.
29.6
N.A.
25.9
N.A.
Protein Similarity:
100
64.1
99.7
93.7
N.A.
97.4
68.3
N.A.
89.2
N.A.
N.A.
N.A.
N.A.
49
N.A.
42.7
N.A.
P-Site Identity:
100
20
93.3
100
N.A.
100
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
26.6
93.3
100
N.A.
100
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
0
0
45
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
56
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
12
0
0
12
12
0
12
0
12
% D
% Glu:
0
0
0
12
0
12
12
0
0
0
0
12
0
0
0
% E
% Phe:
12
12
0
0
0
12
12
0
12
0
45
0
45
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
12
12
0
12
12
12
0
12
0
0
0
12
0
% K
% Leu:
0
12
12
0
12
0
12
12
12
12
0
12
12
56
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
23
0
0
0
0
0
0
45
0
0
0
12
12
% N
% Pro:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
12
0
0
0
0
0
12
0
12
0
0
0
0
12
% Q
% Arg:
45
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% R
% Ser:
12
56
0
23
56
0
0
45
23
0
12
45
0
12
34
% S
% Thr:
0
0
12
0
12
0
0
0
0
0
12
23
12
12
12
% T
% Val:
0
0
0
0
12
12
0
12
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
45
12
23
12
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _